7 Februar 2020

The map to the natural product treasure trove

Leibniz-HKI scientists develop a model of the evolution of biosynthetic pathways

Even small genetic modifications lead to a breathtaking variety of natural substances formed by bacteria.

The team led by the Jena biochemist Pierre Stallforth investigated how the biosynthesis of natural substances changed during evolution. He published the results in the journal “Chemical Science” of the British “Royal Society of Chemistry”. Understanding these mechanisms also means being able to detect specifically effective substances. For example, they could be used as urgently needed new antibiotics or cancer drugs.

Source: Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI), press release, 2020-01-31.

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